A lot can happen on the road to happily ever after... James Franco and Sienna Miller star in a romantic comedy about a marriage that truly is forever! Theirs was the wedding nobody wanted to see… Camille (Miller), the sweetest girl in all of Kentucky, just married the only man she's ever loved, Silas (Franco), a bad boy with a sordid past. When the two set off on the bride’s fantasy honeymoon, events take a sudden, unexpected turn... It’s a long, winding road to Niagara Falls, and Camille is determined to let nothing – not even her own mortality – stand in her way of their happiness. This hilariously endearing, honeymoon-gone-awry road movie also stars the immortal David Carradine as a mystical roving show horseman, Scott Glenn as Camille’s soft-hearted uncle and Ed Lauter as a tough, by-the-book lawman who will stop at nothing to bring Silas in.